Parcourir par auteur "Ramsay, M."
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Genetic Associations With Carotid Intima-Media Thickness Link to Atherosclerosis With Sex-Specific Effects in Sub-Saharan Africans.
Boua, P. R.; Brandenburg, J. T.; Choudhury, A.; Sorgho, H.; Nonterah, E. A.; Agongo, G.; Asiki, G.; Ramsay, M. (National Library of MedicineResearchGate, 2022)Atherosclerosis precedes the onset of clinical manifestations of cardiovascular diseases (CVDs). We used carotid intima-media thickness (cIMT) to investigate genetic susceptibility to atherosclerosis in 7894 unrelated ... -
Genome-Wide Association Study Identifying Novel Risk Variants Associated with Glycaemic Traits in the Continental African AWI-Gen Cohort
Chebii, V. J.; Wade, A. N.; Kisiangani, I.; Crowther, N. J.; Nonterah, E. A.; Agongo, G.; Simayi, Z.; Boua, P. R.; Ramsay, M.; Choudhury, A.; Sengupta, D. (Springer, 2025)Glycaemic traits such as high fasting glucose levels and insulin resistance are positively associated with the risk of type 2 diabetes and other cardiometabolic diseases. Genetic association studies have identified hundreds ... -
Identifying The Prevalence and Correlates of Multimorbidity in Middle-Aged Men and Women: A Cross-Sectional Population-Based Study in Four African Countries.
Micklesfield, L. K.; Munthali, R.; Agongo, G.; Asiki, G.; Boua, P.; Choma, S.S.; Mohamed, S. F.; Ramsay, M. (National Library of MedicineResearchGate, 2023)To determine the prevalence of multimorbidity, to identify which chronic conditions cluster together and to identify factors associated with a greater risk for multimorbidity in sub-Saharan Africa (SSA). Design Cross-sectional, ... -
Incident Type 2 Diabetes and its Risk Factors in Men and Women Aged 40 - 60 Years from Four Sub-Saharan African Countries: Results from the AWI-Gen Study
Chikwati, R. P.; Crowther, N. J.; Ramsay, M.; Micklesfield, L. K.; Norris, S. A.; Seakamela, K. P.; Nonterah, E. A.; Agongo, G.; Mohamed, S. F.; Kisiangani, I.; Boua, P. R.; Wade, A. N. (The Lancet, 2025)The incidence of type 2 diabetes in sub-Saharan Africa is expected to increase, but few longitudinal studies have characterised its risk factors. This study aimed to determine the incidence of type 2 diabetes over 33 481 ... -
Obesity Phenotypes and Dyslipidemia in Adults from Four African Countries: An H3Africa AWI-Gen Study
Nonterah, E. A.; Agongo, G.; Crowther, N. J.; Mohamed, S. F.; Micklesfield, L. K.; Boua, P. R.; Wade, A. N.; Choma, S. S. R.; Sorgho, H.; Kissiangani, I.; Asiki, G.; Ansah, P.; Oduro, A. R.; Norris, S. A.; Tollman, S. M.; Raal, F. J.; Alberts, M.; Ramsay, M. (PLOS ONE, 2025)In this large multi-county SSA study we observed that the mean lipid levels were higher in Southern (Agincourt, Dikgale and Soweto) and Eastern Africa (Nairobi, Kenya) compared to the two sites in West Africa (Nanoro, ... -
Perspectives on Returning Individual and Aggregate Genomic Research Results to Study Participants and Communities in Kenya: A Qualitative Study.
Kisiangani, I.; Mohamed, S. F.; Kyobutungi, C.; Tindana, P.; Ghansah, A.; Ramsay, M.; Asiki, G. (National Library of MedicineBMC Medical Ethics, 2022)Background: A fundamental ethical challenge in conducting genomics research is the question of what and how individual level genetic findings and aggregate genomic results should be conveyed to research participants and ...