KnowHub Repository

KnowHub is a corporate knowledge base that provides the system to identify, capture and publish the most critical organizational knowledge products, both tacit and explicit.

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Recent Submissions

  • Item type: Item , Access status: Open Access ,
    Pedagogies of Inclusion: Case Studies on Gender, STEM and Pedagogy Report
    (APHRC, 2025-10) Simpson, Z.; Matemba, E.; Inglis, H.; Wakiaga, L. A.; Ngware, M.
    This report investigates strategies for implementing inclusive and gender-responsive pedagogy in higher education institutions across Sub-Saharan Africa (SSA). Focusing on Science, Technology, Engineering, and Mathematics (STEM) disciplines, the study synthesizes qualitative insights from four case studies across four universities in Kenya, Tanzania, and Zimbabwe: KCA University, Bindura University of Science Education (BUSE), Women's University in Africa (WUA), and Open University of Tanzania (OUT). The study highlights diverse institutional approaches, including community engagement to foster female participation, bridging access via foundation programs, institutionalizing gender inclusion through dedicated university centers, and utilizing academic development to align with national policy frameworks. The findings emphasize that advancing gender equality in STEM requires sustained institutional commitment, professional faculty development, multi-level stakeholder collaboration, and culturally grounding pedagogical frameworks.
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    Participant engagement and feedback in microbiome projects: a case of AWI-Gen 2
    (bioRXiv, 2026) Nkera-Gutabara, C.; Olubayo, L. A. I.; Oduaran, O. O.; Kisiangani, I.; Khoza, S.; Gama, K.; Maghini, D. G.
    Returning individualized microbiome results in ways that are ethical, comprehensible, and useful remains under-explored in African settings. We nested a multi-site, mixed-methods study within the AWI-Gen Wave 2 gut microbiome sub-study of 1,801 women aged 42 - 86 years to engage the participants and provide feedback. All (1,001) participants from Agincourt and Soweto (South Africa) and Nairobi (Kenya) were invited to feedback meetings: 496 from Agincourt, 87 from Soweto, and 195 from Nairobi responded. Engagement strategies were tailored by site (small-group and home-based sessions, visual metaphors, Foldscopes, and local-language delivery). Using semi-structured discussions and structured observations analysed thematically in MAXQDA under COREQ, five cross-cutting themes emerged: (1) understanding of microbiome reports, (2) emotional responses to feedback, (3) perceived health relevance, (4) trust in research institutions, and (5) suggestions for improving engagement. Culturally grounded explanations and local-language facilitation enhanced comprehension and perceived relevance; English-heavy sessions were associated with more confusion. Most participants expressed satisfaction and described planned or enacted dietary and lifestyle changes, while frustration centred on long delays between sampling and feedback. Trust increased with transparency and individualized return of results but was often conditional on minimizing burdensome procedures such as repeat blood sampling (phlebotomy) and ensuring timely feedback. Engagement was feasible and low-cost (approximately USD 29-59 per participant) with site-specific resource needs. Limitations included constrained generalizability beyond the three study sites. Returning individualized microbiome findings in community settings in Africa is acceptable, feasible, and can motivate health-promoting behaviours when delivered promptly and in culturally and linguistically appropriate ways.
  • Item type: Item ,
    When One Disease is Not the Whole Story: How MADIVA Is Transforming Multimorbidity Care in Nairobi
    (African Population and Health Research Center (APHRC), 2026) Ouma F.; Kisiangani I.; Shete C.; Nderitu D.M.; Iddi S.
    This article details how the Multimorbidity in Africa: Digital Innovation, Visualization and Application (MADIVA) Research Hub is transforming healthcare for urban residents living with multiple chronic conditions in Nairobi's informal settlements. Sub-Saharan Africa faces a growing burden of multimorbidity where individuals simultaneously manage non-communicable diseases like hypertension, diabetes, and mental health conditions alongside infectious diseases yet national health systems remain largely silod and structured for single-disease management. Addressing key challenges in health facility data systems, MADIVA leverages digital innovation and data science by linking fragmented clinical histories with longitudinal demographic surveillance data. This integrated approach strengthens health information systems, enables precise population risk stratification, and informs precision public health strategies to optimize multimorbidity care in resource-constrained urban environments.
  • Item type: Item ,
    The Countdown to 2030 MNH Study Collaboration. Transitions in childbirth care provision: Understanding the rapid rise in institutional delivery in 21 countries of sub-Saharan Africa and the implications for future strategies
    (Elsevier, 2026) Blanchardn AK.; Abajobir, A.; Mutua, M.; Wehrmeister, FC.; Njeri A.; Adero, G.; Aidara, D.; Sandie, A.S.; Ruas, LP.; Blumenberg, C.; Faye, C.; Boerma, T.
    This study evaluates the rapid increase in institutional deliveries across 21 Sub-Saharan African countries to analyze structural shifts in maternal and childbirth care provision. Utilizing cross-country comparative data from the Countdown to 2030 Collaboration, the authors examine national trends in facility-based births, highlighting how health system expansions and policy interventions have driven significant gains in maternal health coverage. However, the analysis demonstrates that rapid volume growth in facility care does not automatically translate into improved health outcomes, as persistent service quality gaps, infrastructure bottlenecks, and regional inequities continue to limit impact. The paper outlines strategic implications for future maternal and newborn health initiatives, emphasizing the critical need to transition from focusing solely on increasing facility access to prioritizing quality of care, emergency obstetric readiness, and equitable healthcare resource distribution.
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    Severity and management of postabortion complications in Kenya: results from a nationally representative cross-sectional survey.
    (BMJ Glob Health, 2026) Giorgio M.; Juma K.; Wado YD.; Owolabi O.; Rich C.; Akuku I.; Mutuku E.; Giuffrida M.; Athero S.; Mueke S.
    A nationally representative cross-sectional survey evaluating 4,666 postabortion care (PAC) cases across 367 health facilities in Kenya demonstrates a significant decline in severe postabortion complications over the past decade, with severe maternal outcomes comprising 1.4% and potentially life-threatening complications accounting for 16.4% of cases, while mild complications doubled to 53.6%. Manual or electric vacuum aspiration remained the predominant uterine evacuation method (65.2%), though 11.7% of patients received no surgical or medical evacuation procedure. Multivariate analysis revealed that economic vulnerabilities including low educational attainment, inability to meet basic household needs, and food insecurity as well as the use of non-recommended abortion methods and experiencing delays by seeking care elsewhere prior to facility arrival, significantly increased the incidence of severe complications. While expanded primary healthcare and increased access to informal medication abortion have substantially reduced severe morbidity compared to 2012 benchmarks, severe complications remain an avoidable risk that necessitates targeted public health interventions to enhance community awareness of safe abortion practices and expand access to affordable reproductive healthcare.