KnowHub Repository

KnowHub is a corporate knowledge base that provides the system to identify, capture and publish the most critical organizational knowledge products, both tacit and explicit.

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Recent Submissions

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    When One Disease is Not the Whole Story: How MADIVA Is Transforming Multimorbidity Care in Nairobi
    (African Population and Health Research Center (APHRC), 2026) Ouma F.; Kisiangani I.; Shete C.; Nderitu D.M.; Iddi S.
    This article details how the Multimorbidity in Africa: Digital Innovation, Visualization and Application (MADIVA) Research Hub is transforming healthcare for urban residents living with multiple chronic conditions in Nairobi's informal settlements. Sub-Saharan Africa faces a growing burden of multimorbidity where individuals simultaneously manage non-communicable diseases like hypertension, diabetes, and mental health conditions alongside infectious diseases yet national health systems remain largely silod and structured for single-disease management. Addressing key challenges in health facility data systems, MADIVA leverages digital innovation and data science by linking fragmented clinical histories with longitudinal demographic surveillance data. This integrated approach strengthens health information systems, enables precise population risk stratification, and informs precision public health strategies to optimize multimorbidity care in resource-constrained urban environments.
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    The Countdown to 2030 MNH Study Collaboration. Transitions in childbirth care provision: Understanding the rapid rise in institutional delivery in 21 countries of sub-Saharan Africa and the implications for future strategies
    (Elsevier, 2026) Blanchardn AK.; Abajobir, A.; Mutua, M.; Wehrmeister, FC.; Njeri A.; Adero, G.; Aidara, D.; Sandie, A.S.; Ruas, LP.; Blumenberg, C.; Faye, C.; Boerma, T.
    This study evaluates the rapid increase in institutional deliveries across 21 Sub-Saharan African countries to analyze structural shifts in maternal and childbirth care provision. Utilizing cross-country comparative data from the Countdown to 2030 Collaboration, the authors examine national trends in facility-based births, highlighting how health system expansions and policy interventions have driven significant gains in maternal health coverage. However, the analysis demonstrates that rapid volume growth in facility care does not automatically translate into improved health outcomes, as persistent service quality gaps, infrastructure bottlenecks, and regional inequities continue to limit impact. The paper outlines strategic implications for future maternal and newborn health initiatives, emphasizing the critical need to transition from focusing solely on increasing facility access to prioritizing quality of care, emergency obstetric readiness, and equitable healthcare resource distribution.
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    Severity and management of postabortion complications in Kenya: results from a nationally representative cross-sectional survey.
    (BMJ Glob Health, 2026) Giorgio M.; Juma K.; Wado YD.; Owolabi O.; Rich C.; Akuku I.; Mutuku E.; Giuffrida M.; Athero S.; Mueke S.
    A nationally representative cross-sectional survey evaluating 4,666 postabortion care (PAC) cases across 367 health facilities in Kenya demonstrates a significant decline in severe postabortion complications over the past decade, with severe maternal outcomes comprising 1.4% and potentially life-threatening complications accounting for 16.4% of cases, while mild complications doubled to 53.6%. Manual or electric vacuum aspiration remained the predominant uterine evacuation method (65.2%), though 11.7% of patients received no surgical or medical evacuation procedure. Multivariate analysis revealed that economic vulnerabilities including low educational attainment, inability to meet basic household needs, and food insecurity as well as the use of non-recommended abortion methods and experiencing delays by seeking care elsewhere prior to facility arrival, significantly increased the incidence of severe complications. While expanded primary healthcare and increased access to informal medication abortion have substantially reduced severe morbidity compared to 2012 benchmarks, severe complications remain an avoidable risk that necessitates targeted public health interventions to enhance community awareness of safe abortion practices and expand access to affordable reproductive healthcare.
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    Rethinking the global health system for a new international order
    (Springer Nature, 2026) Rasanathan, K.; Cloete, K.; Gitahi, G.; Dantes, O. G.; Inoue, H.; Kyobutungi, C.; et al.
    The global health architecture is undergoing a pivotal transition driven by shifting geopolitical dynamics, declining development assistance, and an increasing demand by low- and middle-income countries for sovereign control over their national health priorities. In this commentary, we argue that the current global health system cannot respond effectively to evolving global challenges by merely preserving legacy power structures. Achieving sustainable global health security and equity requires fundamental structural reform that goes beyond institutional reorganization. We advocate for a transformed global health framework anchored in new international cooperation models, decentralized governance, and mutual accountability. Key priorities include shifting from traditional aid-dependency models toward self-sustaining national financing, addressing global structural inequities in resource allocation, and embedding local leadership into the global health research and policy agenda. Re-engineering these mechanisms is essential to building resilient health systems capable of addressing future health emergencies, climate threats, and persistent health disparities in a changing international order.
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    Returned but Not Restored: Experiences of Health and Access to Care Among Return Migrants in Sub-Saharan Africa�A Scoping Review
    (Wiley, 2026) Vange SS.; Asiki, G.; Aikins A-d-G.; Agyemang C.; Girma, E.; Dankyi, EK.; Norredam M.
    Return migrants in Sub-Saharan Africa constitute a diverse population ranging from highly skilled individuals returning voluntarily to vulnerable individuals returning under forced or adverse conditions whose circumstances of return often expose them to severe hardships and health risks. Despite the increasing prevalence of return migration in the region, comprehensive evidence regarding these returnees' health status, mental well-being, and healthcare access remains markedly sparse. This scoping review synthesizes existing literature to assess the health profiles and healthcare-seeking experiences of return migrants in Sub-Saharan Africa. The findings reveal a critical shortage of empirical research, underscoring urgent gaps in data regarding how health vulnerabilities unfold post-return. Addressing these gaps requires expanded empirical inquiry to guide targeted health policies and facilitate effective healthcare re-integration for returnee populations across the region.